PRF (Platelet-rich fibrin) and PRP (Platelet-rich plasma) are naturally derived products that are used to achieve skin rejuvenation. The platelets in the blood’s plasma contain growth factors, which send signals to your body to stimulate tissue repair. When concentrated from a blood sample and injected into the skin, this platelet-containing plasma causes regeneration that leads to new collagen and elastin production. The result is firmer and more youthful-looking skin.
how it works
During your appointment, we use advanced techniques to draw a small sample of your blood, concentrate it with a centrifuge, and extract platelet-rich plasma. At Pivital, we use equipment which concentrates fibrin, a next-generation variation of the PRP technology. Fibrin contains more growth factors than plasma, and releases them over a longer time period.
Platelet-rich fibrin, derived from a sample of your own blood, is reinjected into the treated area, making this treatment natural and chemical free.
Stimulate overall tissue rejuvenation for hair growth in thinning areas and the production of new collagen and elastin for healthier skin.
Improve skin texture and tone, and reduce the appearance of scars, pores, wrinkles, and fine lines.
New collagen formation and hair follicle stimulation take effect for up to six months after, with results lasting anywhere from 18–24 months per treatment.
Package pricing is available when purchasing multiple treatments in advance and combined with microneedling.
Frequently Asked Questions
How many treatments will I need to see results?
Whether combined with microneedling or injected directly, you can expect to see improvement in the thickness and quality of your skin with one treatment. Best results are usually seen with 3–5 treatments.
Hair restoration typically takes 3–6 treatments, each spaced out by 4–6 weeks. The full result is generally seen by six months after the last treatment. Maintenance treatments are typically performed 1–3 times per year ongoing.
How should I prepare for my PRF/PRP treatment?
Avoiding supplements and medications—with the advice of your doctor—that make you bleed more easily for a few days before treatment will reduce your chance of bruising. It’s also imperative to arrive for the treatment well hydrated, as this makes the blood collection easier and also increases the volume of fibrin produced. Drinking extra fluid for 24 hours prior to the procedure will help to ensure you’re well hydrated.
What should I expect during my treatment?
We inject the fibrin into targeted areas of your skin at a precise depth using specialized equipment that enhances the efficacy of your PRF/PRP treatment. Often, we will combine it with a microneedling procedure and synergize the two treatments to increase the overall effectiveness.
How long do results last?
Results gradually take effect over a few weeks, with new collagen forming for up to six months, and can last anywhere from 18 to 24 months per treatment. You can look forward to softer, more radiant skin with the reduced appearance of wrinkles and fine lines.
What is downtime and aftercare like?
Most patients are red (like a sunburn) for the first 24 hours after microneedling with PRF, with a light flaking three to five days afterward and steady ongoing improvements from there. Immediately after the treatment, things look a bit messy due to the treatment and the dried PRF—we recommend heading home directly after your appointment. Leaving the dried PRF on your skin through the first night ensures good uptake of the growth factors.
When injected directly, the PRF can potentially cause some minor local swelling and bruising, which settles in a few days if it occurs. The next morning and next few days only require gentle cleansing and sun avoidance.
What’s the difference between PRF and PRP?
PRF treatments offer more growth factors than PRP, which leads to more stimulation for healthy tissue to grow, and therefore better and more efficient results—this is why we only do PRF treatments at Pivital. Compared to PRP, the PRF also deposits the growth factors over a prolonged period of hours to days, whereas PRP deposits the growth factors in seconds to minutes. PRF requires specialized equipment that is distinct from typical PRP equipment.